“The immune system permeates and regulates organs and tissues across the body, and has diverse roles beyond pathogen control, including in development, tissue homeostasis and repair. The reshaping of the immune system that occurs during aging is therefore highly consequential. In this Focus issue, Nature Aging presents a collection of reviews of and opinions onContinueContinue reading “The immune system offers a window into aging”
Tag Archives: alzheimers
Podcast Dementia Notes
Audio Version: https://overcast.fm/+ABN64PpjuTY Today we will explore the evolving landscape of dementia, with a particular focus on Alzheimer’s disease, Lewy Body dementia, and Frontotemporal dementia. Whether you are a clinician, caregiver, researcher, or someone navigating these conditions with a loved one, this episode aims to inform and empower. We begin with the etiology of Alzheimer’sContinueContinue reading “Podcast Dementia Notes”
Sleep is good, may prevent dementia
How the brain gets rid of its chemical waste through the glymphatics during sleep, via blood vessel oscillations, regulated by norepinephrine. Impeded by Ambien. • Norepinephrine release from the locus coeruleus drives slow vasomotion in NREM sleep • Infraslow norepinephrine oscillations control opposing changes in blood and CSF volumes • Norepinephrine oscillation frequency during NREMContinueContinue reading “Sleep is good, may prevent dementia”
Is Sulforaphane ‘Neuroprotective’?
Recently, the protective effects of sulforaphane on brain health were also considerably studied, where the studies have further extended to several neurological diseases, including Alzheimer’s disease (AD), Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, multiple sclerosis, autism spectrum disorder, and schizophrenia. Animal and cell studies that employ sulforaphane against memory impairment and AD-related pre-clinical biomarkersContinueContinue reading “Is Sulforaphane ‘Neuroprotective’?”
Dr Bob, Brain Mechanic 