Deep cervical lymphatic-venous anastomosis is one of the more interesting failures-in-progress in recent Alzheimer’s research. Theoretically seductive, evidentially threadbare, and already the subject of a regulatory ban in the country where it originated. The theoretical case The rationale rests on the glymphatic–meningeal lymphatic clearance model: cerebrospinal and interstitial fluid carry metabolic waste, including amyloid-β andContinueContinue reading “The Evidence Gap in Deep Cervical Lymphatic Procedures for Alzheimer’s”
Tag Archives: sleep
Rethinking “high HRV”
If you want to increase your HRV, start by forgetting about chasing a big number and focus instead on building a steady, low‑noise baseline. – Many people want higher HRV because they think it proves elite athleticism, but research shows the link is loose and highly individual. – What often separates “high HRV” athletesContinueContinue reading “Rethinking “high HRV””
Sleep is good, may prevent dementia
How the brain gets rid of its chemical waste through the glymphatics during sleep, via blood vessel oscillations, regulated by norepinephrine. Impeded by Ambien. • Norepinephrine release from the locus coeruleus drives slow vasomotion in NREM sleep • Infraslow norepinephrine oscillations control opposing changes in blood and CSF volumes • Norepinephrine oscillation frequency during NREMContinueContinue reading “Sleep is good, may prevent dementia”
Dr Bob, Brain Mechanic 