Which NAD⁺ Booster Is Right for You? In recent years, two vitamin B3 derivatives—Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN)—have emerged as leading contenders in the world of longevity science. Both are precursors to NAD⁺ (nicotinamide adenine dinucleotide), a coenzyme essential for energy production, DNA repair, and healthy cell function. As we age, NAD⁺ levelsContinueContinue reading “Nicotinamide Riboside vs. Nicotinamide Mononucleotide”
Tag Archives: dementia
Podcast Dementia Notes
Audio Version: https://overcast.fm/+ABN64PpjuTY Today we will explore the evolving landscape of dementia, with a particular focus on Alzheimer’s disease, Lewy Body dementia, and Frontotemporal dementia. Whether you are a clinician, caregiver, researcher, or someone navigating these conditions with a loved one, this episode aims to inform and empower. We begin with the etiology of Alzheimer’sContinueContinue reading “Podcast Dementia Notes”
Sleep is good, may prevent dementia
How the brain gets rid of its chemical waste through the glymphatics during sleep, via blood vessel oscillations, regulated by norepinephrine. Impeded by Ambien. • Norepinephrine release from the locus coeruleus drives slow vasomotion in NREM sleep • Infraslow norepinephrine oscillations control opposing changes in blood and CSF volumes • Norepinephrine oscillation frequency during NREMContinueContinue reading “Sleep is good, may prevent dementia”
Is Sulforaphane ‘Neuroprotective’?
Recently, the protective effects of sulforaphane on brain health were also considerably studied, where the studies have further extended to several neurological diseases, including Alzheimer’s disease (AD), Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, multiple sclerosis, autism spectrum disorder, and schizophrenia. Animal and cell studies that employ sulforaphane against memory impairment and AD-related pre-clinical biomarkersContinueContinue reading “Is Sulforaphane ‘Neuroprotective’?”
Dr Bob, Brain Mechanic 