Deep cervical lymphatic-venous anastomosis is one of the more interesting failures-in-progress in recent Alzheimer's research. Theoretically seductive, evidentially threadbare, and already the subject of a regulatory ban in the country where it originated. The theoretical case The rationale rests on the glymphatic–meningeal lymphatic clearance model: cerebrospinal and interstitial fluid carry metabolic waste, including amyloid-β andContinue reading "The Evidence Gap in Deep Cervical Lymphatic Procedures for Alzheimer’s"
‘The Odyssey’ : The Movie of Our Time
Summarized and critiqued from Ezra Klein’s article: Christopher Nolan’s Trojan Horse Tricks are central to “The Odyssey” and Odysseus is a trickster. He is described, in the first line of the story, as the man of many ways or of many wiles or of many turns. He is, depending on the translator, an ingenious man,Continue reading "‘The Odyssey’ : The Movie of Our Time"
Psilocybin’s Lasting Impact
How a Single Dose May Rewire the Brain for Weeks A growing body of research is reshaping how scientists understand psychedelics, not as fleeting, mind-altering experiences, but as catalysts for longer-term biological change. Two recent studies offer compelling evidence that psilocybin, the active compound in “magic mushrooms,” may alter brain communication patterns and immune signalingContinue reading "Psilocybin’s Lasting Impact"
Run an LLM on your iPhone
Check out Bonsai (27B) and Gemma 4 using the Locally AI by LM Studio App on your iPhone 😎 Both run in Locally AI on an iPhone 17 Pro, but they’re built for different jobs, so the “winner” depends on what you’re doing. TL:DR - Bonsai is the stronger pick for reasoning and code; GemmaContinue reading "Run an LLM on your iPhone"
Going to see Pangolins Today
Adapted from a Claude AI query Pangolins are the world’s only truly scaly mammals. Imagine an anteater wearing armor made of the same stuff as your fingernails. Their whole body is covered in overlapping keratin scales, and when threatened they curl into a tight ball. The name comes from the Malay word pengguling, “one whoContinue reading "Going to see Pangolins Today"
Apps and Tech Kit for Safari
Timeshifter - Jet lag app recommended by Amanda, has a 4.7 rating! May be helpful for your trip home 😎 (there is also an alternative free web app Jet Lag Rooster) Stuarts’ African Mammals - Great app for identifying and tracking African mammals (works offline.) Roberts Birds - Wonderful app for identifying and tracking birdsContinue reading "Apps and Tech Kit for Safari"
Does your Carrier support 5G Standalone?
Does Your carrier support 5G Standalone? 5G Standalone (SA) is a 5G network architecture that operates entirely on its own, without relying on older 4G LTE infrastructure. It represents the "true" or fully realized version of 5G technology. To understand why it matters, it helps to look at how 5G was initially rolled out. TheContinue reading "Does your Carrier support 5G Standalone?"
Sweating the Details” OS 27
Extracted from a post from Tidbits (Thanks to Adam Engst) Liquid Glass Updated Liquid Glass Customize Liquid Glass Updated app icons macOS 27 Golden Gate More consistent window positioning persistence across external displays Support for Mac mirroring in 5K resolution More high-resolution and high-refresh-rate display modes for external displays Edge-to-edge sidebars Updated menu bar iconsContinue reading "Sweating the Details” OS 27"
Die With Zero
Bill Perkins’s “Die With Zero” argues that you should organize your money and time so you maximize life experiences rather than die with a large unspent pile of savings. Core thesis and key ideas - Perkins’s central claim is that “the business of life is the acquisition of memories,” so you should consciously spend moneyContinue reading "Die With Zero"
Resistance Exercise Update
A meta-analysis of 192 studies found that untrained individuals doing moderate-load resistance training just twice per week capture ~77% of strength gains, near-maximal muscle growth, and the full mobility benefits of more demanding protocols. The authors use this to define a “minimum effective protocol”: 2 sessions/week, moderate weight (8–12 rep range), 3–4 sets per exercise,Continue reading "Resistance Exercise Update"
